Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 17/20 | 0.58 |
| ▸ | MAPT | P10636 | 15/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022544 | 0.86 | GAA (0.55) | GAAMAPTSMN1; SMN2RXFP1TP53 | |
| SCHEMBL14022614 | 0.86 | GAA (0.58) | GAAMAPTSMN1; SMN2TP53KMT2A | |
| SCHEMBL14022581 | 0.83 | GAA (0.61) | GAAMAPTSMN1; SMN2RXFP1TP53 | |
| SCHEMBL14022636 | 0.83 | MAPT (0.56) | GAAMAPTSMN1; SMN2RXFP1TP53 | |
| SCHEMBL14022535 | 0.82 | MAPT (0.64) | GAAMAPTSMN1; SMN2RXFP1TP53 | |
| SCHEMBL14022623 | 0.82 | GAA (0.58) | GAAMAPTSMN1; SMN2RXFP1TP53 | |
| SCHEMBL2255349 | 0.82 | MAPT (0.66) | GAAMAPTSMN1; SMN2TP53KMT2A | |
| SCHEMBL14022578 | 0.82 | MAPT (0.70) | GAAMAPTSMN1; SMN2TP53KMT2A | |
| SCHEMBL14022501 | 0.80 | GAA (0.58) | GAAMAPTSMN1; SMN2TP53KMT2A | |
| SCHEMBL14022619 | 0.79 | TRIM33 (0.51) | GAAMAPTSMN1; SMN2RXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141239-A1 | IMIDAZOL [1,2-A] PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2008-11-20 | — | — | WO | disclosed |