Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 15/20 | 0.58 |
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | TP53 | P04637 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | PKLR | P30613 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022573 | 0.86 | GAA (0.58) | GAAMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL14022544 | 0.85 | GAA (0.55) | GAAMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL14022508 | 0.83 | GAA (0.58) | GAAMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL14022578 | 0.82 | MAPT (0.70) | GAAMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL14022625 | 0.82 | GAA (0.55) | GAAMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL14022547 | 0.82 | GAA (0.62) | GAAMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL2251722 | 0.81 | MAPT (0.70) | GAAMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL14022584 | 0.79 | GAA (0.58) | GAAMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL14022538 | 0.76 | GAA (0.56) | GAAMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL13474709 | 0.71 | CYP11B1 (0.48) | GAAMAPTTP53SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141239-A1 | IMIDAZOL [1,2-A] PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2008-11-20 | — | — | WO | disclosed |