Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 14/20 | 0.56 |
| ▸ | MAPT | P10636 | 12/20 | 0.56 |
| ▸ | TP53 | P04637 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.55 |
| ▸ | TUBB | P07437 | 2/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.55 |
| ▸ | PKLR | P30613 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022548 | 0.92 | GAA (0.55) | GAAMAPTTP53SMN1; SMN2TUBB4A | |
| SCHEMBL14022576 | 0.91 | GAA (0.54) | GAAMAPTTP53SMN1; SMN2TUBB4A | |
| SCHEMBL14022627 | 0.89 | TUBB4A (0.66) | GAAMAPTTP53SMN1; SMN2TUBB4A | |
| SCHEMBL14022545 | 0.86 | MAPT (0.51) | GAAMAPTTP53SMN1; SMN2TUBB4A | |
| SCHEMBL14022640 | 0.85 | MAPT (0.65) | GAAMAPTTP53SMN1; SMN2TUBB4A | |
| SCHEMBL2252820 | 0.84 | GAA (0.69) | GAAMAPTTP53SMN1; SMN2TUBB4A | |
| SCHEMBL2250661 | 0.84 | GAA (0.77) | GAAMAPTTP53SMN1; SMN2TUBB4A | |
| SCHEMBL14022620 | 0.84 | TUBB4A (0.62) | GAAMAPTTP53SMN1; SMN2TUBB4A | |
| SCHEMBL14022630 | 0.82 | GAA (0.76) | GAAMAPTTP53SMN1; SMN2PKLR | |
| SCHEMBL14022632 | 0.81 | MAPT (0.58) | GAAMAPTTP53SMN1; SMN2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141239-A1 | IMIDAZOL [1,2-A] PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2008-11-20 | — | — | WO | disclosed |