Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.87 |
| ▸ | GAA | P10253 | 11/20 | 0.76 |
| ▸ | TP53 | P04637 | 8/20 | 0.76 |
| ▸ | BRD4 | O60885 | 1/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.65 |
| ▸ | TUBB | P07437 | 2/20 | 0.65 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.65 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.65 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.65 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.65 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.65 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.65 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.65 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.65 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.65 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.65 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.65 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.65 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20286074 | 0.82 | BRD4 (0.82) | MAPTGAATP53BRD4TUBB4A | |
| SCHEMBL27101710 | 0.82 | TRIM33 (0.80) | MAPTGAATP53TUBB4ATUBB | |
| SCHEMBL16416731 | 0.81 | BRD4 (1.00) | MAPTGAATP53BRD4TUBB4A | |
| SCHEMBL14022630 | 0.79 | GAA (0.76) | MAPTGAATP53ALDH1A1KDM4E | |
| SCHEMBL997306 | 0.78 | TP53 (0.87) | MAPTGAATP53ALDH1A1KDM4E | |
| SCHEMBL27101693 | 0.78 | GAA (0.61) | MAPTGAATP53ALDH1A1KDM4E | |
| SCHEMBL27101699 | 0.78 | TRIM33 (0.81) | MAPTGAATP53ALDH1A1KDM4E | |
| SCHEMBL13236225 | 0.76 | MAPT (0.70) | MAPTGAATP53PKMPKLR | |
| SCHEMBL1964838 | 0.76 | TUBB4A (1.00) | MAPTGAATP53BRD4TUBB4A | |
| SCHEMBL998159 | 0.73 | TP53 (0.65) | MAPTGAATP53ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141239-A1 | IMIDAZOL [1,2-A] PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS | ACADIA PHARMACEUTICALS INC. (US) | 2008-11-20 | — | — | WO | disclosed |