Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | CDC7 | O00311 | 7/20 | 0.40 |
| ▸ | XDH | P47989 | 5/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339626 | 0.88 | XDH (0.44) | PIM1CDC7XDHGSK3BCSNK2A1 | |
| SCHEMBL3342410 | 0.85 | CDC7 (0.41) | PIM1CDC7XDHGSK3BCSNK2A1 | |
| SCHEMBL3337518 | 0.82 | CDC7 (0.40) | PIM1CDC7XDHGSK3BCSNK2A1 | |
| SCHEMBL3340028 | 0.82 | CDC7 (0.45) | PIM1CDC7GSK3BCSNK2A1MAPK13 | |
| SCHEMBL3341849 | 0.82 | CDC7 (0.40) | PIM1CDC7XDHGSK3BCSNK2A1 | |
| SCHEMBL3339497 | 0.81 | GSK3B (0.45) | PIM1CDC7GSK3BCSNK2A1MAPK13 | |
| SCHEMBL3345741 | 0.80 | CDC7 (0.45) | PIM1CDC7XDHGSK3BCSNK2A1 | |
| SCHEMBL3342143 | 0.80 | CDC7 (0.41) | PIM1CDC7DAPK3ROCK2PRKD3 | |
| SCHEMBL14023052 | 0.80 | CDC7 (0.40) | PIM1CDC7XDHGSK3BCSNK2A1 | |
| SCHEMBL3338635 | 0.80 | CDC7 (0.40) | PIM1CDC7XDHGSK3BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143759-A1 | PYRIMIDINONES AS CASEIN KINASE II (CK2) MODULATORS | EXELIXIS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |