SCHEMBL1402328

SCHEMBL1402328

c1cc(CSCC2CO2)ccc1CSCC1CO1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.36
CRBN Q96SW2 2/20 0.33
BCHE P06276 2/20 0.32
ACHE P22303 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
RAB9A P51151 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
MGLL Q99685 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10865471 0.90 CRBN (0.44) HDAC1CRBNTDP1CYP3A4RAB9A
SCHEMBL9619682 0.89 CRBN (0.37) HDAC1CRBNTDP1ALDH1A1TP53
SCHEMBL9196423 0.86 CRBN (0.50) CRBNALDH1A1TP53CYP3A4TSHR
SCHEMBL2770834 0.84 HDAC1 (0.33) HDAC1KMT2A
SCHEMBL1402656 0.84 ACHE (0.39) CRBNACHETDP1ALDH1A1TP53
SCHEMBL1402444 0.78 TDP1 (0.38) ACHETDP1ALDH1A1TP53CYP3A4
SCHEMBL14510166 0.75 CRBN (0.38) CRBNALDH1A1SMN1; SMN2RAB9A
SCHEMBL4862284 0.74 ACHE (0.33) ACHEALDH1A1TP53CYP3A4TSHR
SCHEMBL36461 0.74
SCHEMBL8933367 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438147-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL OBTAINED FROM COMPOSITION, AND PLASTIC LENS MITSUI CHEMICALS INC (JP) 2023-06-21 EP disclosed
US-11639413-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2023-05-02 US disclosed
US-11414515-B2 Polymerizable composition for optical material and optical material and plastic lens obtainable from same composition MITSUI CHEMICALS, INC. (JP) 2022-08-16 US disclosed
US-11358354-B2 Process for producing plastic lens and apparatus for producing plastic lens MITSUI CHEMICALS, INC. (JP) 2022-06-14 US disclosed
US-11312857-B2 Polymerizable composition and molded product MITSUI CHEMICALS, INC. (JP) 2022-04-26 US disclosed
EP-2123695-B1 METAL THIETANE COMPOUND, POLYMERIZABLE COMPOSITION COMPRISING THE COMPOUND, RESIN, AND USE OF THE RESIN MITSUI CHEMICALS INC (JP) 2021-06-23 EP disclosed
US-20210079151-A1 METHOD FOR SETTING POLYMERIZATION CONDITION AND METHOD FOR MANUFACTURING OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2021-03-18 US disclosed
EP-3778655-A1 METHOD FOR SETTING POLYMERIZATION CONDITIONS AND METHOD FOR PRODUCING OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2021-02-17 EP disclosed
US-20210017327-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME MITSUI CHEMICALS, INC. (JP) 2021-01-21 US disclosed
EP-3724700-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS AND APPLICATION OF SAME Mitsui Chemicals, Inc. (JP) 2020-10-21 EP disclosed
US-20100063246-A1 POLYMERIZABLE COMPOSITION, RESIN USING THE SAME, OPTICAL COMPONENT AND LENS MITSUI CHEMICALS, INC. (JP) 2010-03-11 US disclosed
EP-2123695-A1 METAL THIETANE COMPOUND, POLYMERIZABLE COMPOSITION COMPRISING THE COMPOUND, RESIN, AND USE OF THE RESIN Mitsui Chemicals, Inc. (JP) 2009-11-25 EP disclosed
EP-2036951-A1 POLYMERIZABLE COMPOSITION, RESIN USING THE SAME, OPTICAL COMPONENT AND LENS Mitsui Chemicals, Inc. (JP) 2009-03-18 EP disclosed
EP-2014700-A1 POLYMERIZABLE COMPOSITION, RESIN USING THE SAME AND OPTICAL COMPONENT Mitsui Chemicals, Inc. (JP) 2009-01-14 EP disclosed
US-7132501-B2 Polymerizable composition containing novel cyclic sulfur compound and resin obtained by curing the polymerizable composition MITSUI CHEMICALS, INC. (JP) 2006-11-07 US disclosed
US-20050215757-A1 Polymerizable composition containing novel cyclic sulfur compound and resin obtained by curing the polymerizable composition MITSUI CHEMICALS, INC. (JP) 2005-09-29 US disclosed
EP-1482002-A1 POLYMERIZABLE COMPOSITION CONTAINING NOVEL CYCLIC SULFUR COMPOUND AND RESIN OBTAINED BY CURING THE POLYMERIZABLE COMPOSITION MITSUI CHEMICALS, INC. (JP) 2004-12-01 EP disclosed
EP-0785194-B1 Episulfide compound MITSUBISHI GAS CHEMICAL CO (JP) 2002-07-17 EP disclosed
US-5945504-A Episulfide compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1999-08-31 US disclosed
EP-0785194-A1 Episulfide compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-07-23 EP disclosed