Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436958 | 0.84 | POLB (0.44) | SMN1; SMN2L3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL14023298 | 0.77 | MAPT (0.53) | GAASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL13806334 | 0.77 | GAA (0.36) | GAASMN1; SMN2MAPTPOLBKMT2A | |
| SCHEMBL19999715 | 0.75 | KDM5A (0.33) | GAAALDH1A1MAPTPOLB | |
| SCHEMBL12436979 | 0.74 | ALDH1A1 (0.47) | ALDH1A1POLBTSHRKMT2AMEN1 | |
| SCHEMBL12436920 | 0.73 | GAA (0.46) | GAASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL190928 | 0.72 | CYP1A2 (0.48) | SMN1; SMN2 | |
| SCHEMBL22051142 | 0.71 | ALDH1A1 (0.44) | GAASMN1; SMN2L3MBTL1ALDH1A1HTT | |
| SCHEMBL23541545 | 0.70 | SMN1; SMN2 (0.49) | GAASMN1; SMN2ALDH1A1MAPTPOLB | |
| SCHEMBL12436957 | 0.70 | GAA (0.71) | GAASMN1; SMN2L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133344-A2 | PIPERIDINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-06 | — | — | WO | disclosed |