Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23402352 | 0.82 | BCHE (0.55) | ALDH1A1MAPTLMNAGAAALOX15 | |
| SCHEMBL23403713 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL23399086 | 0.80 | KDM4E (0.42) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL23398632 | 0.80 | BCHE (0.56) | ALDH1A1MAPTLMNAGAAALOX15 | |
| SCHEMBL23403374 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL23402467 | 0.76 | BCHE (0.51) | ALDH1A1MAPTLMNAGAAALOX15 | |
| SCHEMBL23402766 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL23401224 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL23401070 | 0.74 | BCHE (0.53) | ALDH1A1MAPTLMNAGAAALOX15 | |
| SCHEMBL680008 | 0.74 | ALDH1A1 (0.75) | ALDH1A1MAPTSMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141385-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-11-27 | — | — | WO | disclosed |