Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 7/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28260509 | 0.92 | PLK1 (0.66) | PLK1HDAC6HDAC2HDAC8KMT2A | |
| SCHEMBL15705715 | 0.88 | HDAC6 (0.74) | PLK1HDAC6HDAC2HDAC8KMT2A | |
| SCHEMBL250247 | 0.87 | HDAC6 (0.80) | PLK1HDAC6HDAC2HDAC8HPGD | |
| SCHEMBL15705705 | 0.87 | HDAC1 (0.78) | PLK1HDAC6HDAC2HDAC8HPGD | |
| SCHEMBL10153931 | 0.86 | PLK1 (0.70) | PLK1HDAC6HDAC2HDAC8KMT2A | |
| SCHEMBL1121661 | 0.86 | PLK1 (1.00) | PLK1HDAC6HDAC2HDAC8HPGD | |
| SCHEMBL15017778 | 0.86 | PLK1 (0.70) | PLK1HDAC6HDAC2HDAC8KMT2A | |
| SCHEMBL16610174 | 0.85 | TSHR (0.63) | PLK1KMT2AHPGDTSHRHTT | |
| SCHEMBL14391650 | 0.85 | PLK1 (0.68) | PLK1HDAC6HDAC2HDAC8KMT2A | |
| SCHEMBL2643236 | 0.85 | PLK1 (0.68) | PLK1HDAC6HDAC2HDAC8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261153-A1 | PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |