Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.80 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.80 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | PLK1 | P53350 | 8/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | MMP13 | P45452 | 1/20 | 0.61 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16198923 | 0.92 | HDAC6 (0.70) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL14115137 | 0.92 | HDAC6 (0.70) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL23933223 | 0.89 | HDAC8 (0.67) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL159659 | 0.89 | HDAC2 (0.67) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL131434 | 0.89 | MMP13 (0.77) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL479724 | 0.89 | HDAC2 (0.67) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL19631295 | 0.89 | HDAC6 (1.00) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL2425658 | 0.89 | HDAC2 (0.67) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL2643668 | 0.89 | HDAC8 (0.67) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL192212 | 0.87 | HDAC2 (0.64) | HDAC6HDAC8HDAC2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119487019-A | Piperazine derivatives for HIV therapy | VIIV保健公司 | 2025-02-18 | — | — | CN | claimed |
| US-20240254148-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) | 2024-08-01 | — | — | US | claimed |
| US-20240254148-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) | 2024-08-01 | — | — | US | disclosed |
| WO-2024154213-A1 | THERMOSETTING RESIN COMPOSITION, STATOR COIL, AND ROTARY ELECTRIC MACHINERY | 三菱電機株式会社 | 2024-07-25 | — | — | WO | disclosed |
| EP-3411069-B1 | HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2024-07-10 | — | — | EP | disclosed |
| US-20240016937-A1 | COMPOSITION CONTAINING NUCLEIC ACID MOLECULE STABLY | TORAY INDUSTRIES, INC. (JP) | 2024-01-18 | — | — | US | disclosed |
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| US-20230338906-A1 | SEPARATION MEMBRANE | NITTO DENKO CORPORATION (JP) | 2023-10-26 | — | — | US | disclosed |
| US-11764019-B2 | Arc extinguishing chamber base of molded case circuit breaker | LS ELECTRIC CO., LTD. (KR) | 2023-09-19 | — | — | US | disclosed |
| EP-4215262-A1 | SEPARATION MEMBRANE | NITTO DENKO CORPORATION (JP) | 2023-07-26 | — | — | EP | disclosed |
| US-20230192844-A1 | HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH | 2023-06-22 | — | — | US | disclosed |
| US-20060189774-A1 | Modifiable polyunsaturated polymers and processes for their preparation | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2006-08-24 | — | — | US | disclosed |
| EP-1411033-A1 | Method for producing titanium oxide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-04-21 | — | — | EP | disclosed |
| EP-0306025-B1 | Process for producing polyarylene sulfide | IDEMITSU PETROCHEMICAL CO (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-5225450-A | Thermoplastic resin foil formes by extrusion, heat treatment and adhesion | SCHREINER LUCHTVAART GROEP B.V. (NL) | 1993-07-06 | — | — | US | disclosed |
| EP-0345855-B1 | PROCESS FOR ADHERING MATERIALS TOGETHER | Schreiner Luchtvaart Groep B.V. (NL) | 1991-07-31 | — | — | EP | disclosed |
| EP-0345855-A1 | Process for adhering materials together | Schreiner Luchtvaart Groep B.V. (NL) | 1989-12-13 | — | — | EP | disclosed |
| EP-0306025-A2 | Process for producing polyarylene sulfide | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1989-03-08 | — | — | EP | disclosed |
| US-4259258-A | Preparation of bis-n-chloramides of cycloaliphatic carboxylic acids | AKZONA INCORPORATED (US) | 1981-03-31 | — | — | US | disclosed |
| US-4142029-A | Bis-tetrazoles as chemical blowing agents for foaming thermoplastic resins | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192844-A1 | HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF | CD2, CD47, KLK3 | HDAC6 401/4885HDAC8 642/4885HDAC2 1086/4885 |
| US-20240254148-A1 | METHODS OF MAKING METAL-ORGANIC FRAMEWORKS WITH PRE-LIGANDS | HCAR3, POF1B, HCAR1 | HDAC6 2466/4885HDAC8 466/4885HDAC2 923/4885 |
| US-20240016937-A1 | COMPOSITION CONTAINING NUCLEIC ACID MOLECULE STABLY | NSUN2, POLRMT, POLN | HDAC6 2660/4885HDAC8 3513/4885HDAC2 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.