Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463455 | 0.93 | TLR2 (0.50) | TLR2BCHEACHEKMT2AMDM2 | |
| SCHEMBL30973621 | 0.93 | TLR2 (0.50) | TLR2BCHEACHEKMT2AMDM2 | |
| SCHEMBL12231705 | 0.93 | TLR2 (0.50) | TLR2BCHEACHEKMT2AMDM2 | |
| SCHEMBL12254867 | 0.93 | TLR2 (0.57) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL14026797 | 0.90 | KMT2A (0.47) | KMT2AMDM2MDM4TP53 | |
| SCHEMBL30684555 | 0.89 | TLR2 (0.58) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL14433000 | 0.88 | TLR2 (0.59) | TLR2BCHEACHEKMT2AMDM2 | |
| SCHEMBL16048758 | 0.87 | TLR2 (0.51) | TLR2BCHEACHEKMT2AMDM2 | |
| SCHEMBL31688554 | 0.87 | TLR2 (0.59) | TLR2KMT2AMDM2MDM4TP53 | |
| SCHEMBL16048760 | 0.87 | TLR2 (0.51) | TLR2BCHEACHEKMT2AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446102-B2 | Antibacterial amide macrocycles IV | AICURIS GMBH & CO. KG (DE) | 2008-11-04 | — | — | US | disclosed |
| US-20080076745-A1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | AICURIS GMBH & CO. KG (DE) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076745-A1 | ANTIBACTERIAL AMIDE MACROCYCLES IV | NOD2, AAAS, AADAC | TLR2 53/4885BCHE 1864/4885ACHE 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.