Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.55 |
| ▸ | CALML3 | P27482 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | SDHA | P31040 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395112 | 0.92 | MAOA (0.62) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1393697 | 0.92 | MAOA (0.54) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1394946 | 0.90 | MAOA (0.51) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL14432606 | 0.88 | MAOA (0.60) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1394782 | 0.87 | MAOA (0.57) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL3165898 | 0.87 | MAOA (0.59) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL3165893 | 0.87 | MAOA (0.59) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL3176596 | 0.87 | MAOA (0.59) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL3176599 | 0.87 | MAOA (0.59) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL13148535 | 0.86 | MAOA (0.49) | MAOACALML3MAOBPTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456206-B2 | Biaryl heterocyclic compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-25 | — | — | US | disclosed |