Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CBX7 | O95931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4822755 | 0.93 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3HRH3ALDH1A1 | |
| SCHEMBL4824477 | 0.80 | OPRL1 (0.41) | ALDH1A1OPRM1OPRL1DHFRIFNAR1 | |
| SCHEMBL14027243 | 0.75 | HRH3 (0.34) | HRH3ALDH1A1DHFRIFNAR1LMNA | |
| SCHEMBL4818176 | 0.73 | MAPT (0.35) | ALDH1A1OPRM1OPRL1DHFRIFNAR1 | |
| SCHEMBL4818055 | 0.71 | CHRM1 (0.48) | KMT2A | |
| Formic Acid SCHEMBL4911312 | 0.69 | SMN1; SMN2 (0.35) | ALDH1A1OPRM1OPRL1DHFRLMNA | |
| SCHEMBL4824586 | 0.67 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3ALDH1A1DHFR | |
| SCHEMBL4824600 | 0.67 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3ALDH1A1DHFR | |
| SCHEMBL6742634 | 0.66 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1OPRM1 | |
| SCHEMBL4904964 | 0.60 | HTR6 (0.46) | SLC6A4ALDH1A1LMNANPY1RMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269217-A1 | Melanocortin-4 receptor binding compounds and methods of use thereof | MC4R, MC5R, MC3R | SLC6A2 438/4885SLC6A4 137/4885SLC6A3 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.