SCHEMBL14028501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15935924	0.86	CYP2D6 (0.40)	CALCRLTNKSCHRM2CHRM4CHRM1
	SCHEMBL13351353	0.83	CALCRL (0.38)	CALCRLCHRM2CHRM4CHRM1CHRM3
	SCHEMBL12372810	0.82	OPRM1 (0.52)	CALCRLTNKSTNKS2OPRM1OPRD1
	SCHEMBL14046422	0.82	CYP2D6 (0.46)	CALCRLCHRM1OPRM1CYP2D6CYP2C9
	SCHEMBL13054218	0.81	CHRM2 (0.46)	CHRM2CHRM4CHRM1CHRM3OPRM1
	SCHEMBL1196924	0.80	JAK2 (0.43)	CALCRLTNKSTNKS2CHRM2CHRM4
	SCHEMBL12372559	0.78	TNKS (0.51)	HSD11B1TNKSTNKS2CHRM2CHRM4
	SCHEMBL14028503	0.76	MAP3K11 (0.39)	CALCRLTNKSTNKS2OPRM1OPRD1
	SCHEMBL12372558	0.75	TNKS (0.51)	CALCRLHSD11B1TNKSTNKS2CHRM2
	SCHEMBL14028502	0.75	CALCRL (0.42)	CALCRLHSD11B1TNKSTNKS2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.