Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | S100B | P04271 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028549 | 0.91 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL14028570 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL8340483 | 0.84 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL6334634 | 0.82 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL2126641 | 0.81 | CYP3A4 (0.53) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL8681665 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL4953967 | 0.78 | CETP (0.42) | TDP1CETPHTTTSHRSMN1; SMN2 | |
| SCHEMBL14028540 | 0.78 | CYP3A4 (0.41) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL10495591 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TDP1THRBALOX15 | |
| SCHEMBL6376391 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TDP1THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |