Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8755135 | 0.90 | ALDH1A1 (0.48) | KMT2AMEN1KDM4ESMN1; SMN2POLB | |
| SCHEMBL6232531 | 0.84 | SMN1; SMN2 (0.50) | KMT2AMEN1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL18222955 | 0.81 | KMT2A (0.50) | KMT2AMEN1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL28779833 | 0.81 | KDM4E (0.50) | KMT2AMEN1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL14004238 | 0.80 | RARB (0.41) | KDM4EHRH3SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL11789508 | 0.79 | KDM4E (0.49) | KMT2AMEN1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL9588954 | 0.79 | ALDH1A1 (0.54) | KMT2AMEN1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL1527681 | 0.79 | KDM4E (0.51) | KMT2AMEN1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL15581380 | 0.77 | MEN1 (0.50) | KMT2AMEN1KDM4EHRH3SMN1; SMN2 | |
| SCHEMBL12391999 | 0.77 | MEN1 (0.50) | KMT2AMEN1KDM4EHRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7438830-B2 | Mixtures for producing transparent plastics, transparent plastics, method for producing the same and the use thereof | ROEHM GMBH & CO. KG (DE) | 2008-10-21 | — | — | US | disclosed |
| US-7419619-B2 | Mixtures for producing transparent plastics, transparent plastics and method for their production and use | ROEHM GMBH & CO. KG (DE) | 2008-09-02 | — | — | US | disclosed |