Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 5/20 | 0.47 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974539 | 0.89 | GRIN2D (0.51) | FURINPCSK6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29974717 | 0.89 | GRIN2D (0.51) | FURINPCSK6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29974325 | 0.89 | GRIN2D (0.51) | FURINPCSK6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29510734 | 0.89 | FURIN (0.52) | FURINPCSK6SIRT6SIRT1CTSL | |
| SCHEMBL29510727 | 0.87 | FURIN (0.54) | FURINPCSK6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29510589 | 0.87 | FURIN (0.54) | FURINPCSK6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29510666 | 0.85 | GNPAT (0.52) | FURINPCSK6SIRT6SIRT1CTSL | |
| SCHEMBL38660722 | 0.84 | GRIN2D (0.57) | FURINPCSK6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL38659567 | 0.84 | GRIN2D (0.57) | FURINPCSK6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL7865517 | 0.82 | GRIN2D (0.50) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439225-B2 | Substances K01-B0171 and process for producing the same | THE KITASATO INSTITUTE (JP) | 2008-10-21 | — | — | US | disclosed |
| US-7439225-B2 | Substances K01-B0171 and process for producing the same | THE KITASATO INSTITUTE (JP) | 2008-10-21 | — | — | US | disclosed |