Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.52 |
| ▸ | FURIN | P09958 | 4/20 | 0.51 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 2/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29510734 | 0.92 | FURIN (0.52) | GNPATFURINPCSK6SIRT6SIRT1 | |
| SCHEMBL29510589 | 0.89 | FURIN (0.54) | FURINPCSK6ECE1SIRT6SIRT1 | |
| SCHEMBL29510727 | 0.89 | FURIN (0.54) | FURINPCSK6ECE1SIRT6SIRT1 | |
| SCHEMBL30374879 | 0.87 | FOLH1 (0.50) | GNPATFURINPCSK6FOLH1CPB2 | |
| SCHEMBL30873802 | 0.86 | GNPAT (0.53) | GNPATFURINPCSK6FOLH1ECE1 | |
| SCHEMBL30320474 | 0.85 | BACE1 (0.46) | FURINPCSK6FOLH1CPB2CTSD | |
| SCHEMBL14028952 | 0.85 | FURIN (0.47) | FURINPCSK6SIRT6SIRT1CTSL | |
| SCHEMBL29399159 | 0.85 | SIRT6 (0.51) | GNPATFURINPCSK6SIRT6SIRT1 | |
| SCHEMBL30608459 | 0.84 | FURIN (0.50) | GNPATFURINPCSK6CPB2SIRT6 | |
| SCHEMBL30446955 | 0.83 | FOLH1 (0.49) | GNPATFOLH1ECE1CPB2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980134-A1 | BIOACTIVE PEPTIDES AND COMPOSITIONS COMPRISING THEM | Espikem S.r.l. (IT) | 2022-04-13 | — | — | EP | disclosed |