Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | GLUL | P15104 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14029190 | 0.86 | BTN3A1 (0.43) | ALDH1A1BTN3A1GLULLMNACHRM5 | |
| SCHEMBL17753880 | 0.84 | ALDH1A1 (0.52) | ALDH1A1LMNAAPOBEC3AAPOBEC3GCHRM5 | |
| SCHEMBL17754085 | 0.82 | LPAR3 (0.50) | ALDH1A1LMNAAPOBEC3AAPOBEC3GCHRM5 | |
| SCHEMBL4953298 | 0.82 | LPAR3 (0.50) | ALDH1A1LMNAAPOBEC3AAPOBEC3GCHRM5 | |
| SCHEMBL7903599 | 0.82 | LPAR3 (0.50) | ALDH1A1LMNAAPOBEC3AAPOBEC3GCHRM5 | |
| SCHEMBL17753846 | 0.78 | ALDH1A1 (0.54) | ALDH1A1LMNACHRM5CHRM1CHRM3 | |
| SCHEMBL189930 | 0.74 | ALDH1A1 (0.74) | ALDH1A1LMNAAPOBEC3AAPOBEC3GCHRM5 | |
| SCHEMBL4893786 | 0.73 | ALDH1A1 (0.46) | ALDH1A1LMNACHRM5CHRM1CHRM3 | |
| SCHEMBL17754084 | 0.72 | LPAR3 (0.57) | ALDH1A1LMNAAPOBEC3AAPOBEC3GCHRM5 | |
| SCHEMBL4441760 | 0.72 | ALDH1A1 (0.70) | ALDH1A1LMNAAPOBEC3AAPOBEC3GCHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432277-B2 | Phosphorus-containing macrocycles | ARAID GENE THERAPEUTICS, INC. (US) | 2008-10-07 | — | — | US | disclosed |