Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SLC14A1 | Q13336 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14507422 | 0.83 | IKBKB (0.45) | ALDH1A1HPGDMAPTPOLBMEN1 | |
| SCHEMBL243572 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL4621697 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL24630402 | 0.78 | FFAR1 (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL381164 | 0.78 | MAPK14 (0.52) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL26041025 | 0.78 | MAPK14 (0.33) | KDM4EALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL4605599 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HPGDSMN1; SMN2HTTLMNA | |
| SCHEMBL102004 | 0.77 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL5445499 | 0.76 | MAPK14 (0.51) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL26242918 | 0.75 | KDM4E (0.39) | KDM4EALDH1A1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249301-A1 | Regioselective Process for Preparing Benzimidazole Thiophenes | SMITHKLINE BEECHAM CORPORATION | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249301-A1 | Regioselective Process for Preparing Benzimidazole Thiophenes | CYP3A4, CYP2C19, CYP2B6 | KDM4E 787/4885ALDH1A1 178/4885HPGD 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.