Ginkolide B

Ginkolide B

SCHEMBL14029435

C[C@@H]1C(=O)O[C@H]2[C@@H](O)[C@@]34[C@H]5C[C@@H](C(C)(C)C)[C@]36[C@@H](OC(=O)[C@@H]6O)O[C@@]4(C(=O)O5)[C@@]12O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 4/20 1.00
GLRA1 P23415 3/20 1.00
GLRA2 P23416 3/20 1.00
CYP2C9 P11712 1/20 1.00
HSD17B10 Q99714 1/20 1.00
GUSB P08236 1/20 1.00
KMT2A Q03164 2/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
MEN1 O00255 1/20 0.67
KDM4E B2RXH2 1/20 0.66
MAPK1 P28482 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ginkolide B SCHEMBL13702797 1.00 PTAFR (1.00) PTAFRGLRA1GLRA2CYP2C9HSD17B10
Ginkolide B SCHEMBL464784 1.00 PTAFR (1.00) PTAFRGLRA1GLRA2CYP2C9HSD17B10
Ginkolide B SCHEMBL29495629 1.00 PTAFR (1.00) PTAFRGLRA1GLRA2CYP2C9HSD17B10
Ginkolide B SCHEMBL16407904 1.00 PTAFR (1.00) PTAFRGLRA1GLRA2CYP2C9HSD17B10
Ginkolide B SCHEMBL464783 1.00 PTAFR (1.00) PTAFRGLRA1GLRA2CYP2C9HSD17B10
Ginkolide B SCHEMBL29410795 1.00 PTAFR (1.00) PTAFRGLRA1GLRA2CYP2C9HSD17B10
Ginkolide B SCHEMBL12714280 1.00 PTAFR (1.00) PTAFRGLRA1GLRA2CYP2C9HSD17B10
Ginkolide B SCHEMBL14279903 1.00 PTAFR (1.00) PTAFRGLRA1GLRA2CYP2C9HSD17B10
SCHEMBL13960075 0.94 PTAFR (0.89) PTAFRGLRA1GLRA2CYP2C9HSD17B10
SCHEMBL13702667 0.94 PTAFR (0.89) PTAFRGLRA1GLRA2CYP2C9HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120078718-A Oral brain-targeted nanoemulsion and preparation method and application thereof 四川大学 2025-06-03 CN claimed
CN-120053426-A Bilobalide composition and application thereof in preparation of medicine for preventing and/or treating hemolytic jaundice 山东新时代药业有限公司 2025-05-30 CN claimed
CN-119907666-A Application of ginkgolide in preparing medicament for preventing or treating diabetes and diabetic complications 成都百裕制药股份有限公司 2025-04-29 CN claimed
CN-119679847-A Myocardial protection composition and application thereof in medicine 新疆医科大学第一附属医院 2025-03-25 CN claimed
CN-119656121-A Gastric floating controlled release preparation 江苏康缘药业股份有限公司 2025-03-21 CN claimed
CN-119656113-A Self-nanoemulsion drug release system 江苏康缘药业股份有限公司 2025-03-21 CN claimed
CN-119433784-A Mildew-proof polyester yarn and preparation method thereof 泰信达化纤(盐城)有限公司 2025-02-14 CN claimed
CN-115112783-B Construction and application of ginkgo leaf detection method and multi-component simultaneous reflection fingerprint 江苏康缘药业股份有限公司 2024-12-17 CN claimed
CN-118948910-A Preparation method of ginkgo extract for treating or preventing thrombosis 廖良坤 2024-11-15 CN claimed
CN-108904343-B Ginkgo leaf composition for delaying aging and preparation method and application thereof 北京工商大学 2024-11-08 CN claimed
CN-110433157-B Application of ginkgolide in preparation of medicine for preventing and/or treating vertigo 成都百裕制药股份有限公司 2022-10-18 CN claimed
CN-110396098-B Preparation and medicinal use of bilobalide B azacyclic derivative and salt thereof 复旦大学 2022-10-14 CN claimed
CN-115112783-A Ginkgo leaf detection method and construction and application of fingerprint spectrum with simultaneous reflection of multiple components 江苏康缘药业股份有限公司 2022-09-27 CN claimed
CN-115047099-A Method for rapidly determining content of total terpene lactones in elution process of ginkgo leaf extract 上海上药杏灵科技药业股份有限公司 2022-09-13 CN claimed
CN-111983077-B Detection method of ginkgo dipyridamole injection preparation 贵州益佰制药股份有限公司 2022-08-30 CN claimed
CN-114949112-A Pet hair loss prevention additive, preparation, food and health product 真爱生命生物技术(重庆)有限公司 2022-08-30 CN claimed
CN-217180825-U Quick check out test set of bilobalide B 江苏恒天生物科技有限公司 2022-08-12 CN claimed
CN-114786725-A Compositions containing endogenous cannabinoid mimetics and anti-inflammatory compounds, methods of making and uses thereof 药妆研究有限责任公司 2022-07-22 CN claimed
CN-108926556-B Composition containing ginkgolide and medical application thereof 成都百裕制药股份有限公司 2022-07-05 CN claimed
CN-111249274-B Application of ginkgolide B in preparation of glioma cell activity inhibitor 杭州师范大学 2022-04-01 CN claimed