Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 0.66 |
| ▸ | PLEC | Q15149 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 7/20 | 0.64 |
| ▸ | DRD2 | P14416 | 6/20 | 0.64 |
| ▸ | HTR2B | P41595 | 6/20 | 0.64 |
| ▸ | HTR6 | P50406 | 6/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178071 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30278505 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10471429 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25042463 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7176983 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25042462 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9820435 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25042461 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL257961 | 1.00 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| Methyl Alcohol SCHEMBL27814674 | 0.99 | HSD17B10 (0.98) | HSD17B10KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CACYBP, TBCB, MYCBP | HSD17B10 982/4885KDM4E 4553/4885ALDH1A1 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.