Sugi Predict

Sugi Predict / Targets / TBCB

TBCB

Tubulin-folding cofactor B · Q99426 · TBCB on Sugi Atlas →

0 patent compounds predicted against TBCB, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TBCB by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Glycerol-Phenylbutyrate Treatment in Children With MCT Mutation (Allan-Herndon- Dudley Syndrome) PHASE2/PHASE3UNKNOWN
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
The Nutritional Supplement Phosphatidylserine in Patients With Familial Dysautonomia PHASE2COMPLETED
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome PHASE2RECRUITING
An Open-label, Single Center, Single Participant Study of an Experimental Antisense Oligonucleotide Treatment for TUBB4A-related Leukodystrophy PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Single Participant Study of an Experimental ASO Treatment for TUBB4A-related Leukodystrophy PHASE1/PHASE2ENROLLING_BY_INVITATION
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
The Safety and Immunogenicity of a TB Vaccine; MVA85A, in Healthy Volunteers Who Are Infected With HIV PHASE1COMPLETED
A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors PHASE1COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies PHASE1COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Transcranial Photobiomodulation for the Treatment of Pediatric Depression nanWITHDRAWN
The Role of TBC1D4 in Exercise- and Insulin-induced Glucose Metabolism in Human Skeletal Muscle nanCOMPLETED
Natural History of Acquired and Inherited Bone Marrow Failure Syndromes nanRECRUITING
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
PCD New Gene Discovery nanCOMPLETED
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Genome-wide Epistasis for Cardiovascular Severity in Marfan Study nanUNKNOWN
TBP Survey Among Respiratory Physicians nanCOMPLETED
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia nanRECRUITING
Transcranial Magnetic Stimulation (TMS) Studies of Dystonia nanCOMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
PET/CT Imaging in Carriers of TTR Mutations nanNOT_YET_RECRUITING
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Natural History Study and Establishment of a Biorepository-TANGO2-related Disorder nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a TBCB binder may also engage these)

ProteinNameSimilarity
Q9D1E6 — 1.000 Q9D1E6 →
Q5E951 — 1.000 Q5E951 →
Q67Z52 — 0.995 Q67Z52 →
Q20728 — 0.986 Q20728 →
Q8K268 — 0.982 Q8K268 →
Q10235 — 0.981 Q10235 →
Q7SH49 — 0.981 Q7SH49 →
F4J8C6 — 0.981 F4J8C6 →
P31669 — 0.981 P31669 →
B3MPC0 — 0.981 B3MPC0 →
Q9CQN1 — 0.981 Q9CQN1 →
USP7 Ubiquitin carboxyl-terminal hydrolase 7 0.981 landscape →
Q4VSI4 — 0.981 Q4VSI4 →
Q84WW3 — 0.981 Q84WW3 →
Q7ZU90 — 0.981 Q7ZU90 →
Q86T65 — 0.980 Q86T65 →
Q8WTJ4 — 0.980 Q8WTJ4 →
Q5XIR9 — 0.980 Q5XIR9 →
TRAP1 Heat shock protein 75 kDa, mitochondrial 0.980 landscape →
Q75LU5 — 0.980 Q75LU5 →
Q5SMU7 — 0.980 Q5SMU7 →
P10686 — 0.980 P10686 →
B4G7U3 — 0.980 B4G7U3 →
PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 0.980 landscape →
Q6CMF8 — 0.980 Q6CMF8 →
B6ZLK2 — 0.980 B6ZLK2 →
Q62077 — 0.980 Q62077 →
B3N8L3 — 0.980 B3N8L3 →
P27967 — 0.980 P27967 →
P27124 — 0.980 P27124 →