Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825300 | 0.84 | TAAR1 (0.58) | TAAR1CXCR4CYP2D6CYP3A4HRH1 | |
| SCHEMBL17887890 | 0.83 | CXCR4 (0.48) | TAAR1CXCR4CYP2D6CYP3A4HRH1 | |
| SCHEMBL274490 | 0.82 | TAAR1 (0.59) | TAAR1CYP2D6TSHRSMN1; SMN2LMNA | |
| SCHEMBL14968968 | 0.81 | TAAR1 (0.49) | TAAR1CXCR4CYP2D6CYP3A4HRH1 | |
| SCHEMBL14968969 | 0.81 | TAAR1 (0.49) | TAAR1CXCR4CYP2D6CYP3A4HRH1 | |
| SCHEMBL14004804 | 0.80 | CXCR4 (0.48) | TAAR1CHRM2CXCR4CYP2D6TSHR | |
| SCHEMBL12807569 | 0.79 | TAAR1 (0.53) | TAAR1CXCR4CYP2D6CYP3A4HRH1 | |
| SCHEMBL28211846 | 0.79 | TAAR1 (0.46) | TAAR1CXCR4CYP2D6CYP3A4HRH1 | |
| SCHEMBL825460 | 0.77 | TAAR1 (0.51) | TAAR1CXCR4CYP2D6CYP3A4HRH1 | |
| SCHEMBL12193521 | 0.77 | TAAR1 (0.56) | TAAR1CXCR4CYP2D6CYP3A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | TAAR1 1220/4885CHRM2 1822/4885CXCR4 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.