Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14032834 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRFFAR1ALOX15SMN1; SMN2 | |
| SCHEMBL19221360 | 0.89 | FFAR1 (0.51) | ALDH1A1TSHRFFAR1SMN1; SMN2LDHA | |
| SCHEMBL24915328 | 0.89 | ALDH1A1 (0.54) | ALDH1A1TSHRFFAR1ALOX15SMN1; SMN2 | |
| SCHEMBL7131204 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR1ALOX15SMN1; SMN2 | |
| SCHEMBL26172590 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR1ALOX15SMN1; SMN2 | |
| SCHEMBL7131207 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR1ALOX15SMN1; SMN2 | |
| SCHEMBL12086478 | 0.86 | ALDH1A1 (0.58) | ALDH1A1TSHRFFAR1ALOX15SMN1; SMN2 | |
| SCHEMBL14032673 | 0.86 | GLA (0.49) | ALDH1A1FFAR1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL14032600 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR1ALOX15SMN1; SMN2 | |
| SCHEMBL10702376 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TSHRFFAR1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439258-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD (CA) | 2008-10-21 | — | — | US | disclosed |
| US-7439258-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD (CA) | 2008-10-21 | — | — | US | disclosed |