Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111017 | 0.86 | TLR4 (0.43) | TLR4ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL11956606 | 0.83 | ALDH1A1 (0.40) | TLR4ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL14730720 | 0.83 | TLR4 (0.43) | TLR4ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL21733525 | 0.82 | TLR4 (0.45) | TLR4ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL15684078 | 0.82 | ALDH1A1 (0.45) | TLR4ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL857663 | 0.80 | ALDH1A1 (0.49) | TLR4ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL15416184 | 0.79 | MAPT (0.43) | TLR4ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL15416529 | 0.79 | ALDH1A1 (0.45) | TLR4ALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL31756478 | 0.78 | KDM4E (0.33) | ALDH1A1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL14731543 | 0.76 | TLR4 (0.39) | TLR4ALDH1A1MAPTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439263-B2 | Pyrrolidine and thiazolidine compounds | LES LABORATOIRES SERVIER (FR) | 2008-10-21 | — | — | US | disclosed |