Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.59 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040446 | 1.00 | AR (0.59) | ARCTSBLMNAALDH1A1NPSR1 | |
| SCHEMBL4048739 | 0.93 | AR (0.63) | ARCTSBLMNAALDH1A1MAPT | |
| SCHEMBL4038981 | 0.93 | AR (0.63) | ARCTSBLMNAALDH1A1MAPT | |
| SCHEMBL4042740 | 0.93 | AR (0.63) | ARCTSBLMNAALDH1A1MAPT | |
| SCHEMBL4219668 | 0.91 | AR (0.57) | ARCTSBLMNAALDH1A1MAPT | |
| SCHEMBL6376932 | 0.91 | AR (0.57) | ARCTSBLMNAALDH1A1MAPT | |
| SCHEMBL6212517 | 0.91 | AR (0.57) | ARCTSBLMNAALDH1A1MAPT | |
| SCHEMBL6492936 | 0.87 | AR (0.77) | ARCTSBALDH1A1 | |
| SCHEMBL5097882 | 0.87 | AR (0.57) | ARALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL5088693 | 0.87 | AR (0.57) | ARCTSBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432267-B2 | Fused cyclic modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMAPNY (US) | 2008-10-07 | — | — | US | disclosed |