SCHEMBL6492936

SCHEMBL6492936

O=C1C2C3CC(CN3C(=O)Oc3ccc(F)cc3)N2C(=O)N1c1ccc([N+](=O)[O-])c2ccccc12

nearest known ligand 0.77

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AR P10275 12/20 0.77
CTSB P07858 2/20 0.34
MGLL Q99685 1/20 0.33
CHRNA7 P36544 1/20 0.33
HTR3A P46098 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
TLR9 Q9NR96 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14033476 0.87 AR (0.59) ARCTSBALDH1A1
SCHEMBL4040446 0.87 AR (0.59) ARCTSBALDH1A1
SCHEMBL14033658 0.85 AR (0.70) ARCTSB
SCHEMBL5088693 0.85 AR (0.57) ARCTSBKMT2AALDH1A1
SCHEMBL14032868 0.85 AR (0.57) ARCHRNA7HTR3A
SCHEMBL4042538 0.85 AR (0.62) ARMEN1KMT2ANPC1ALDH1A1
SCHEMBL6375514 0.84 AR (0.65) ARCTSBMEN1KMT2ATLR9
SCHEMBL4039836 0.84 AR (0.65) ARCTSBMEN1KMT2ATLR9
SCHEMBL5099264 0.84 AR (0.65) ARCTSBMEN1KMT2ATLR9
SCHEMBL5092450 0.84 AR (0.65) ARCTSBMEN1KMT2ATLR9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050256048-A1 Selective androgen receptor modulators and methods for their identification, design and use SALVATI MARK E 2005-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256048-A1 Selective androgen receptor modulators and methods for their identification, design and use AR, FSHR, LHCGR AR 1/4885CTSB 3810/4885MGLL 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.