Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146557 | 0.64 | MEN1 (0.32) | ALDH1A1 | |
| SCHEMBL12588782 | 0.60 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL802733 | 0.59 | ALDH1A1 (0.40) | ALDH1A1PKM | |
| SCHEMBL14517986 | 0.59 | CRBN (0.30) | — | |
| SCHEMBL13618092 | 0.59 | CRBN (0.30) | — | |
| SCHEMBL25255933 | 0.57 | ALDH1A1 (0.44) | ALDH1A1PKM | |
| SCHEMBL14033952 | 0.56 | MEN1 (0.30) | ALDH1A1 | |
| SCHEMBL13878863 | 0.55 | DUSP3 (0.35) | ALDH1A1PKM | |
| SCHEMBL6850987 | 0.54 | GSK3A (0.44) | ALDH1A1 | |
| SCHEMBL12588779 | 0.53 | GAA (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442804-B2 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |
| US-20070100135-A1 | Process for the preparation of furopyrroles | CIBA SPECIALTY CHEMICALS CORPORATION | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100135-A1 | Process for the preparation of furopyrroles | CCND3, C1S, CCNL2 | ALDH1A1 2024/4885PKM 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.