⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28559756 | 0.96 | — | — | |
| Acetone SCHEMBL2428423 | 0.73 | — | — | |
| SCHEMBL306102 | 0.72 | — | — | |
| SCHEMBL28193228 | 0.72 | — | — | |
| SCHEMBL1843586 | 0.72 | — | — | |
| SCHEMBL12997105 | 0.72 | — | — | |
| Acetamide SCHEMBL6731735 | 0.70 | — | — | |
| Acetone SCHEMBL28344975 | 0.70 | ALDH1A1 (0.53) | — | |
| Acetic Acid SCHEMBL4942868 | 0.70 | FFAR3 (0.58) | — | |
| Acetic Acid SCHEMBL1342560 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478841-B | By being freeze-dried and the cysteine conjugates of hyaluronic acid of mercaptan-alkene clicking chemistry preparation and its synthetic method and application | 海南大学 | 2019-02-19 | — | — | CN | claimed |
| CN-108148115-A | A kind of cyclic peptide new synthetic method and its application in drug development | 中国药科大学 | 2018-06-12 | — | — | CN | claimed |
| CN-106478841-A | The cysteine conjugates of hyaluronic acid prepared with mercaptan alkene clicking chemistry by lyophilization and its synthetic method and application | 海南大学 | 2017-03-08 | — | — | CN | claimed |
| CN-102844305-B | Antibacterial isoquinolin-3-ylurea derivatives | ACTELION PHARMACEUTICALS LTD | 2014-07-02 | — | — | CN | claimed |
| CN-103429596-A | Degradation of penicillin compounds | DSM SINOCHEM PHARM NL BV | 2013-12-04 | — | — | CN | claimed |
| CN-101693738-B | Method for synthesizing terlipressin by solid-phase oxidization and cyclization | SHENZHEN HYBIO PHARMACEUTICAL | 2013-02-13 | — | — | CN | claimed |
| CN-102844305-A | Antibacterial isoquinolin-3-ylurea derivatives | ACTELION PHARMACEUTICALS LTD | 2012-12-26 | — | — | CN | claimed |
| CN-102459160-A | Lysine compounds and their use in site- and chemoselective modification of peptides and proteins | STICHTING HET NL KANKER I | 2012-05-16 | — | — | CN | claimed |
| CN-102112449-A | Phenyl or pyridinyl substituted indazoles derivatives | ASTRAZENECA AB | 2011-06-29 | — | — | CN | claimed |
| CN-102037007-A | Selective exosite inhibition of PAPP-A activity against IGFBP-4 | UNIV AARHUS | 2011-04-27 | — | — | CN | claimed |
| EP-2291359-A1 | PHENYL OR PYRIDINYL SUBSTITUTED INDAZOLES DERIVATIVES | AstraZeneca AB (SE) | 2011-03-09 | — | — | EP | claimed |
| US-20100080786-A1 | Phenyl or Pyridinyl Substituted Indazoles Derivatives | ASTRAZENECA AB (SE) | 2010-04-01 | — | — | US | claimed |
| WO-2009142569-A1 | PHENYL OR PYRIDINYL SUBSTITUTED INDAZOLES DERIVATIVES | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | WO | claimed |
| CN-1051547-C | Beta-lactams derivative and its prep. and use | HOFFMANN LA ROCHE (CH) | 2000-04-19 | — | — | CN | claimed |
| CN-1132752-A | Beta-lactam derivatives, process for their preparation and their use | HOFFMANN LA ROCHE (CH) | 1996-10-09 | — | — | CN | claimed |
| CN-1055925-A | Pyridine derivate and preparation method thereof | ICI PLC (GB) | 1991-11-06 | — | — | CN | claimed |
| CN-86104835-A | VASOPRESSIN ANTAGONISTS | — | 1986-12-17 | — | — | CN | claimed |
| CN-117209447-A | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| US-4857630-A | Hyperbranched polyarylene | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-08-15 | — | — | US | disclosed |
| CN-86104835-A | VASOPRESSIN ANTAGONISTS | — | 1986-12-17 | — | — | CN | disclosed |