Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14509230 | 0.85 | TSHR (0.49) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL4901429 | 0.81 | KMT2A (0.58) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL4901427 | 0.81 | KMT2A (0.58) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL13092658 | 0.81 | TSHR (0.45) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL4909547 | 0.79 | KMT2A (0.62) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL4909540 | 0.79 | KMT2A (0.62) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL10678505 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL13609922 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL13609911 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL10442259 | 0.76 | ALDH1A1 (0.40) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432400-B2 | Biphenylene compounds | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432400-B2 | Biphenylene compounds | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-10-07 | — | — | US | disclosed |