Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14033741 | 0.83 | CHEK2 (0.49) | NPC1RAB9ASMN1; SMN2CYP1A2CNR1 | |
| SCHEMBL8918196 | 0.81 | NR4A2 (0.50) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL17541593 | 0.76 | CYP1A2 (0.53) | CYP1A2HPGDPDGFRBPDGFRAMGAM | |
| SCHEMBL14033839 | 0.75 | CYP2A6 (0.56) | NPC1RAB9ACNR1MEN1KMT2A | |
| SCHEMBL438735 | 0.73 | CYP1A2 (0.57) | NPC1RAB9ASMN1; SMN2CYP1A2MEN1 | |
| SCHEMBL29375315 | 0.73 | PDGFRB (0.66) | NPC1RAB9ASMN1; SMN2CYP1A2CNR1 | |
| SCHEMBL29060493 | 0.73 | PDGFRB (0.66) | NPC1RAB9ASMN1; SMN2CYP1A2CNR1 | |
| SCHEMBL2607479 | 0.72 | CYP1A2 (0.57) | CYP1A2CNR2HPGDPDGFRBPDGFRA | |
| SCHEMBL30474837 | 0.72 | CYP1A2 (0.52) | RAB9ACYP1A2HPGDPDGFRBPDGFRA | |
| SCHEMBL372349 | 0.72 | CYP1A2 (0.52) | RAB9ACYP1A2HPGDPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |