Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306728 | 0.98 | CYP1A2 (0.55) | CYP1A2PDGFRBPDGFRAKDRMGAM | |
| Phosphoric Acid SCHEMBL28789787 | 0.89 | KDR (0.57) | CYP1A2KDRMGAMALDH1A1NPC1 | |
| SCHEMBL6711050 | 0.84 | ALDH1A1 (0.52) | CYP1A2PDGFRBPDGFRAKDRMGAM | |
| SCHEMBL1008611 | 0.82 | MAPT (0.50) | CYP1A2PDGFRBPDGFRAKDRMGAM | |
| SCHEMBL30842280 | 0.78 | ALDH1A1 (0.44) | CYP1A2PDGFRBPDGFRAMGAMALDH1A1 | |
| SCHEMBL29060493 | 0.78 | PDGFRB (0.66) | CYP1A2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL29375315 | 0.78 | PDGFRB (0.66) | CYP1A2PDGFRBPDGFRACYP2A6BIRC5 | |
| SCHEMBL27191399 | 0.78 | PDGFRB (0.61) | CYP1A2PDGFRBPDGFRAMGAMCYP2A6 | |
| SCHEMBL30702581 | 0.77 | PDGFRB (0.59) | CYP1A2PDGFRBPDGFRAKDRALDH1A1 | |
| SCHEMBL7157574 | 0.77 | PDGFRB (0.59) | CYP1A2PDGFRBPDGFRAKDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117160451-A | Platinum-tin bimetallic catalyst for quinoline compound reduction methylation and preparation method and application thereof | 浙江大学衢州研究院 | 2023-12-05 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| CN-105753838-A | Novel high-regioselectivity amination method of quinoline derivatives | 安阳师范学院 | 2016-07-13 | — | — | CN | claimed |
| US-4795621-A | CATALYST OF QUINOLINE COMPOUND AND METAL COMPOUND | SHIN NISSO KAKO CO., LTD. (JP) | 1989-01-03 | — | — | US | claimed |
| US-20260083723-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS | TORAY INDUSTRIES, INC. (JP) | 2026-03-26 | — | — | US | disclosed |
| US-12570639-B2 | Tetrahydroquinoline derivative and medicinal use thereof | TORAY INDUSTRIES, INC. (JP) | 2026-03-10 | — | — | US | disclosed |
| US-12551478-B2 | Quinoline derivative having indoleamine-2,3-dioxygenase inhibitory activity | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2026-02-17 | — | — | US | disclosed |
| EP-4545079-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS | Toray Industries, Inc. (JP) | 2025-04-30 | — | — | EP | disclosed |
| US-20250115578-A1 | AROMATIC FUSED RING NAV1.8 INHIBITOR, AND USE THEREOF | CHENGDU KANGHONG PHARMACEUTICAL CO., LTD. (CN) | 2025-04-10 | — | — | US | disclosed |
| CN-119403554-A | Therapeutic or prophylactic agent for amyotrophic lateral sclerosis | 东丽株式会社 | 2025-02-07 | — | — | CN | disclosed |
| EP-4455130-A1 | AROMATIC FUSED RING NAV1.8 INHIBITOR, AND USE THEREOF | Chengdu Kanghong Pharmaceutical Co., Ltd. (CN) | 2024-10-30 | — | — | EP | disclosed |
| US-4797148-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| US-4795621-A | CATALYST OF QUINOLINE COMPOUND AND METAL COMPOUND | SHIN NISSO KAKO CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| US-4493838-A | Medicaments containing derivatives of 3-chloro-quinoline | PHARMINDUSTRIE (FR) | 1985-01-15 | — | — | US | disclosed |
| US-4493838-A | Medicaments containing derivatives of 3-chloro-quinoline | PHARMINDUSTRIE (FR) | 1985-01-15 | — | — | US | disclosed |
| US-4405789-A | ANTICONVULSANT, ANTIANXIETY | PHARMINDUSTRIE (FR) | 1983-09-20 | — | — | US | disclosed |
| EP-0035925-A1 | 3-Chloroquinoline derivatives, processes for their preparation and medicaments containing them | PHARMUKA LABORATOIRES (FR) | 1981-09-16 | — | — | EP | disclosed |
| US-4212937-A | NITROGEN-CONTAINING HETEROCYCLIC BASE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-07-15 | — | — | US | disclosed |
| US-3968066-A | Oil and water repellent textile composition containing a fluorochemical polyurethane resin and a quaternary ammonium salt | CIBA-GEIGY CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12551478-B2 | Quinoline derivative having indoleamine-2,3-dioxygenase inhibitory activity | IDO2, IDO1, HDAC2 | CYP1A2 499/4885PDGFRB 3467/4885PDGFRA 3883/4885 |
| US-20260083723-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS | AIFM2, GPX1, SOD1 | CYP1A2 4489/4885PDGFRB 3258/4885PDGFRA 3519/4885 |
| US-12570639-B2 | Tetrahydroquinoline derivative and medicinal use thereof | AIFM2, GPX1, GPX4 | CYP1A2 3812/4885PDGFRB 2960/4885PDGFRA 3340/4885 |
| US-20250115578-A1 | AROMATIC FUSED RING NAV1.8 INHIBITOR, AND USE THEREOF | SCN8A, SCN10A, SCN7A | CYP1A2 2188/4885PDGFRB 2789/4885PDGFRA 2388/4885 |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | CYP1A2 2553/4885PDGFRB 4797/4885PDGFRA 4488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.