Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14033267 | 0.96 | CHRM1 (0.39) | CHRM2CHRM1ALDH1A1CHRM3CHRNB2 | |
| SCHEMBL231365 | 0.86 | CHRM1 (0.42) | CHRM2CHRM1ALDH1A1CHRM3CHRNB2 | |
| SCHEMBL7811397 | 0.86 | CHRM1 (0.42) | CHRM2CHRM1ALDH1A1CHRM3CHRNB2 | |
| SCHEMBL231364 | 0.86 | CHRM1 (0.42) | CHRM2CHRM1ALDH1A1CHRM3CHRNB2 | |
| Hydrochloric Acid SCHEMBL6169933 | 0.84 | ALDH1A1 (0.43) | CHRM2CHRM1ALDH1A1CHRM3CHRNB2 | |
| Hydrochloric Acid SCHEMBL7701666 | 0.84 | ALDH1A1 (0.43) | CHRM2CHRM1ALDH1A1CHRM3CHRNB2 | |
| Carbamic Acid SCHEMBL7831819 | 0.76 | ALDH1A1 (0.42) | CHRM2CHRM1ALDH1A1CHRM3CHRNB2 | |
| Carbamic Acid SCHEMBL7831823 | 0.76 | ALDH1A1 (0.42) | CHRM2CHRM1ALDH1A1CHRM3CHRNB2 | |
| SCHEMBL14501858 | 0.75 | CHRM2 (0.35) | CHRM2CHRM1ALDH1A1CHRM3 | |
| SCHEMBL5376258 | 0.75 | CHRM2 (0.35) | CHRM2CHRM1ALDH1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442694-B2 | Diazabicyclic compounds useful in the treatment of CNS and other disorders | PFIZER INC (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442694-B2 | Diazabicyclic compounds useful in the treatment of CNS and other disorders | PFIZER INC (US) | 2008-10-28 | — | — | US | disclosed |