Succinic Acid

Succinic Acid

SCHEMBL140347

N.N.O=C(O)CCC(=O)O

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4

The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.90
EGLN1 Q9GZT9 4/20 0.90
ALKBH5 Q6P6C2 1/20 0.90
SUCNR1 Q9BXA5 1/20 0.90
SLC22A6 Q4U2R8 1/20 0.61
SLC15A2 Q16348 1/20 0.60
MAPK1 P28482 1/20 0.60
SLC13A3 Q8WWT9 1/20 0.60
OR51E2 Q9H255 1/20 0.60
TSHR P16473 3/20 0.57
NFKB1 P19838 1/20 0.57
PMP22 Q01453 1/20 0.57
HDAC3 O15379 2/20 0.53
HDAC1 Q13547 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC8 Q9BY41 2/20 0.53
FFAR3 O14843 1/20 0.53
KDM4E B2RXH2 3/20 0.53
KDM5C P41229 3/20 0.53
PHF8 Q9UPP1 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL5738709 1.00 LMNA (0.90) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL9189068 1.00 LMNA (0.90) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL14834482 1.00 LMNA (0.90) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL140348 1.00
Succinic Acid SCHEMBL9189067 1.00 LMNA (0.90) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL7096341 0.95 LMNA (0.82) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL987258 0.95 LMNA (0.82) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL11219926 0.95 LMNA (0.82) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL21925048 0.95 LMNA (0.82) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL11196387 0.95 LMNA (0.82) LMNAEGLN1ALKBH5SUCNR1SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3001 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071024-A1 POLYPROPIOLACTONES AND METHODS OF PREPARATION NOVOMER INC (US) 2026-03-12 US claimed
US-20250320128-A1 ZSM-5 MOLECULAR SIEVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF, HYDROTREATMENT CATALYST, HYDRODEWAXING CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2025-10-16 US claimed
EP-4065236-B1 METHOD FOR THE DECOLORIZATION OF KERATIN MATERIAL THAT HAS BEEN DYED USING A PIGMENT HENKEL AG & CO KGAA (DE) 2025-06-11 EP claimed
CN-119842584-A Engineering bacterium for high-yield beta-alanine by taking secret plasmid as expression vector and double-carbon source fermentation method 浙江工业大学 2025-04-18 CN claimed
CN-119818469-A Succinate nano-drug, preparation method and application thereof 中国科学院长春应用化学研究所 2025-04-15 CN claimed
CN-119531191-B Water-blocking paper bag and preparation method and application thereof 湖南省长城铭泰新材料科技有限公司 2025-04-11 CN claimed
CN-119774648-A Method for preparing nano calcium carbonate from phosphogypsum 合肥中亚环保科技有限公司 2025-04-08 CN claimed
CN-119615164-A High-selectivity SiO (silicon dioxide) without damaging Cu and Ta barrier layers2Etching solution 湖北兴福电子材料股份有限公司 2025-03-14 CN claimed
CN-115976586-B Forward and reverse pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2025-03-14 CN claimed
EP-3083040-B1 HIGH-CONCENTRATION SILVER SOLUTIONS FOR ETHYLENE OXIDE CATALYST PREPARATION SCIENT DESIGN LLC (US) 2025-03-05 EP claimed
EP-0354220-B1 MULTI-STAGE PROCESS FOR REDUCING THE CONCENTRATION OF POLLUTANTS IN AN EFFLUENT FUEL TECH, INC. (US) 1993-04-21 EP claimed
US-5175137-A Copper halide as adsorbers for carbon monoxide or olefins on a carbon or metal oxide support AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-12-29 US claimed
US-5126310-A Selective adsorbent for carbon monoxide or ethylene AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-06-30 US claimed
EP-0472180-A2 Highly dispersed cuprous compositions AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-02-26 EP claimed
US-4902488-A TREATMENT WITH ORGANIC ACID AMMONIUM SALT FUEL TECH, INC. (US) 1990-02-20 US claimed
US-4766076-A USING WATER SOLUBLE SALT OF DIBASIC ALIPHATIC ACIDS THE STATE OF OREGON ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) 1988-08-23 US claimed
EP-0178903-A2 Improved tellurium imaging composition and film including imide or ammonium salt ENERGY CONVERSION DEVICES, INC. (US) 1986-04-23 EP claimed
US-4232046-A Liquid starch-urea ruminant feed and method of preparing same KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 1980-11-04 US claimed
US-4038141-A METHODS FOR EXTRACTING AND PURIFYING KALLIDINOGENASE SEIKAGAKU KOGYO CO. LTD. (JA) 1977-07-26 US claimed
US-3988483-A Liquid starch-urea ruminant feed and method of producing same THE KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 1976-10-26 US claimed