⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15335431 | 0.80 | TP53 (0.42) | — | |
| SCHEMBL14034844 | 0.78 | TP53 (0.37) | — | |
| SCHEMBL1705841 | 0.78 | — | — | |
| SCHEMBL12216602 | 0.78 | — | — | |
| SCHEMBL24572038 | 0.75 | GGT1 (0.39) | — | |
| SCHEMBL20017013 | 0.74 | — | — | |
| SCHEMBL1745887 | 0.74 | — | — | |
| SCHEMBL20095382 | 0.73 | TP53 (0.33) | — | |
| SCHEMBL5364973 | 0.72 | TP53 (0.35) | — | |
| Formic Acid SCHEMBL30381140 | 0.72 | CYP1A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634455-B2 | Amino diacids containing peptide modifiers | CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) | 2023-04-25 | — | — | US | disclosed |
| WO-2021119249-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-06-17 | — | — | WO | disclosed |
| US-20190177362-A1 | AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS | CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) | 2019-06-13 | — | — | US | disclosed |
| WO-2008138570-A1 | MEDICAL DEVICES COMPRISING A CO-POLYMER OF A MODIFIED POLYAMIDE AND A POLYETHER | ABBOTT LABORATORIES VASCULAR ENTERPRISES LIMITED (IE) | 2008-11-20 | — | — | WO | disclosed |