GGT1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL349849	0.53	9/20
SCHEMBL349850	0.53	9/20
SCHEMBL215522	0.72	4/20
SCHEMBL215523	0.72	4/20
SCHEMBL602426	0.62	4/20
SCHEMBL29289	0.56	4/20
SCHEMBL29291	0.56	4/20
Hydrochloric Acid (SCHEMBL318746)	0.56	4/20
Hydrochloric Acid (SCHEMBL318747)	0.56	4/20
SCHEMBL439378	0.55	4/20
SCHEMBL600881	0.55	4/20
SCHEMBL472936	0.52	4/20
Serine (SCHEMBL527447)	0.52	4/20
Norvaline (SCHEMBL542602)	0.52	4/20
SCHEMBL56998	0.52	4/20
Glutamine (SCHEMBL7452)	0.50	4/20
Glutamine (SCHEMBL7453)	0.50	4/20
Glutamine (SCHEMBL60360)	0.50	4/20
Glutamic Acid (SCHEMBL135757)	0.50	4/20
SCHEMBL224295	0.50	4/20

Clinical trials — most relevant to GGT1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Paracetamol Study in Patients With Low Muscle Mass	PHASE4	UNKNOWN
Cysteine Supplementation in Critically Ill Neonates	PHASE2/PHASE3	UNKNOWN
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma	PHASE3	COMPLETED
Prevent Cardiac Surgery Associated AKI Trial	PHASE2	RECRUITING
Effect of Acetaminophen and N-Acetylcysteine on Liver Metabolism on Homocystinuria	PHASE1/PHASE2	SUSPENDED
Broccoli Sprout Extracts Trial to See if NRF2 is Enhanced by Sulforaphane Treatment in Patients With COPD	PHASE2	COMPLETED
Effect of Combined Antioxidant Therapy on Oxidative Stress Markers and Inflammatory Cytokines in Patients With Tinnitus	PHASE2	UNKNOWN
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy	PHASE2	RECRUITING
Crizotinib in High-Risk Uveal Melanoma Following Definitive Therapy	PHASE2	COMPLETED
A Preliminary Study to Evaluate Cysteamine Therapy in Human Subjects With Non-Alcoholic Steatohepatitis (NASH)	PHASE1/PHASE2	COMPLETED
Tolerability of Enteral NAC in Infants	PHASE1	NOT_YET_RECRUITING
Neoadjuvant Chemoradiotherapy Followed By Surgery in Treating Patients With Limited-Stage Small Cell Lung Cancer	PHASE1	COMPLETED
A Study of RGLS4326 in Patients With Autosomal Dominant Polycystic Kidney Disease	PHASE1	COMPLETED
A Study of MCARH109 and MCARH125 in People With Multiple Myeloma	PHASE1	ACTIVE_NOT_RECRUITING
Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis	PHASE1	COMPLETED
The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels	PHASE1	COMPLETED
A Study to Assess Safety and Tolerability of GS1-144 in Healthy Volunteers	PHASE1	COMPLETED
Vorinostat in Patients With Class 2 High Risk Uveal Melanoma	EARLY_PHASE1	WITHDRAWN
Effects of Green Tea Extract (GTE) on Systemic Oxidative and Antioxidative Status in Chinese Patients With Stable Asthma	nan	COMPLETED
Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans	nan	COMPLETED
Broccoli and Vascular Health Study	nan	COMPLETED
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS	nan	RECRUITING
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione	nan	COMPLETED
Checkpoint Inhibitor-induced Liver Injury	nan	RECRUITING
Autologous Tumor-Infiltrating Lymphocyte (GT307 Injection ) for Treatment of Patients With Solid Tumours	nan	RECRUITING
High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia	nan	COMPLETED
Cancer and Hearing Loss Related in Children	nan	COMPLETED
Predictors of Neonatal Necrotizing Enterocolitis	nan	COMPLETED
Biomarker for Gilbert Disease (BioGilbert)	nan	WITHDRAWN
Mechanisms of Response to Diesel Exhaust in Subjects With Asthma	nan	WITHDRAWN

Related proteins — ESM-2 sequence neighbours (a GGT1 binder may also engage these)

Protein	Name	Similarity
A6NGU5	—	1.000	A6NGU5 →
P36268	—	0.999	P36268 →
Q60928	—	0.998	Q60928 →
P20735	—	0.997	P20735 →
P07314	—	0.991	P07314 →
B5MD39	—	0.963	B5MD39 →
Q9BX51	—	0.963	Q9BX51 →
Q14390	—	0.962	Q14390 →
Q9QWE9	—	0.953	Q9QWE9 →
Q9Z2A9	—	0.952	Q9Z2A9 →
P36269	—	0.946	P36269 →
Q680I5	—	0.941	Q680I5 →
D4B387	—	0.940	D4B387 →
P0DPU3	—	0.940	P0DPU3 →
Q9CZR2	—	0.939	Q9CZR2 →
O77564	—	0.939	O77564 →
O35409	—	0.938	O35409 →
P17439	—	0.938	P17439 →
P0DPU6	—	0.937	P0DPU6 →
P15693	—	0.936	P15693 →
F8S0Z7	—	0.936	F8S0Z7 →
Q2KHZ8	—	0.935	Q2KHZ8 →
P21588	—	0.934	P21588 →
P70627	—	0.934	P70627 →
P19111	—	0.934	P19111 →
P24822	—	0.934	P24822 →
Q05927	—	0.933	Q05927 →
Q9CAR5	—	0.933	Q9CAR5 →
B6EWW8	—	0.933	B6EWW8 →
Q17QK3	—	0.933	Q17QK3 →