Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 10/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10205410 | 0.92 | ABCB1 (0.48) | KDM4EKMT2AALDH1A1TP53MAPK1 | |
| SCHEMBL14008335 | 0.91 | KDM4E (0.51) | KDM4EKMT2AALDH1A1HPGDGAA | |
| SCHEMBL14035116 | 0.90 | KDM4E (0.50) | KDM4EKMT2AALDH1A1HPGDGAA | |
| SCHEMBL14008331 | 0.89 | KDM4E (0.48) | KDM4EKMT2AALDH1A1HPGDGAA | |
| SCHEMBL14008329 | 0.89 | KDM4E (0.50) | KDM4EKMT2AALDH1A1HPGDGAA | |
| SCHEMBL28520428 | 0.89 | ABCB1 (0.48) | KDM4EKMT2AALDH1A1HPGDGAA | |
| SCHEMBL28265381 | 0.85 | PTPN11 (0.43) | ALDH1A1TP53MAPK1ABCB1EGFR | |
| SCHEMBL28265380 | 0.85 | PTPN11 (0.43) | ALDH1A1TP53MAPK1ABCB1EGFR | |
| SCHEMBL10205413 | 0.85 | PTPN11 (0.54) | KMT2AMEN1POLBABCB1USP2 | |
| SCHEMBL21974831 | 0.84 | ABCB1 (0.44) | KDM4EKMT2AALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275215-A1 | Fluorescein-Based Compounds And Their Use For Peptide Synthesis | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275215-A1 | Fluorescein-Based Compounds And Their Use For Peptide Synthesis | DNPEP, ANPEP, PEPD | KDM4E 4808/4885KMT2A 4722/4885ALDH1A1 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.