SCHEMBL28265381

SCHEMBL28265381

CCCCCCCCC=CCCCCCCCCOC(=O)c1ccccc1-c1c2ccc(=O)cc-2oc2cc(OCCCCCCCC/C=C\CCCCCCCC)ccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 1/20 0.43
ABCB1 P08183 1/20 0.43
USP2 O75604 2/20 0.42
CFTR P13569 1/20 0.42
PAX8 Q06710 1/20 0.42
ATM Q13315 1/20 0.42
GOPC Q9HD26 1/20 0.42
ESR1 P03372 1/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28265380 1.00 PTPN11 (0.43) PTPN11ABCB1USP2CFTRPAX8
SCHEMBL10205410 0.93 ABCB1 (0.48) PTPN11ABCB1USP2CFTRPAX8
SCHEMBL28544248 0.92 ABCB1 (0.40) PTPN11ABCB1USP2CFTRPAX8
SCHEMBL28544250 0.92 ABCB1 (0.40) PTPN11ABCB1USP2CFTRPAX8
SCHEMBL20600870 0.86 USP2 (0.53) ABCB1USP2CFTRPAX8ATM
SCHEMBL20600864 0.86 USP2 (0.53) ABCB1USP2CFTRPAX8ATM
SCHEMBL30388412 0.86 USP2 (0.53) ABCB1USP2CFTRPAX8ATM
SCHEMBL14035115 0.85 KDM4E (0.51) ABCB1USP2CFTRPAX8ATM
SCHEMBL20600850 0.84 USP2 (0.55) ABCB1USP2CFTRPAX8ATM
SCHEMBL10205413 0.84 PTPN11 (0.54) PTPN11ABCB1USP2CFTRPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109276723-A A kind of spherical shape pomegranate structure shape nano particle and its preparation method and application 华中科技大学 2019-01-29 CN disclosed