SCHEMBL14035154

SCHEMBL14035154

CCN(CC)C/C=C(\F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8858731 0.74 THRB (0.50) THRB
SCHEMBL21297507 0.71 THRB (0.38) THRB
SCHEMBL6852227 0.70 THRB (0.34) THRB
SCHEMBL6852226 0.70 THRB (0.34) THRB
SCHEMBL6853477 0.70 THRB (0.34) THRB
SCHEMBL6853478 0.70 THRB (0.34) THRB
SCHEMBL1220456 0.70
SCHEMBL1220458 0.70
SCHEMBL8755172 0.69 THRB (0.31) THRB
SCHEMBL8755175 0.69 THRB (0.31) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080293997-A1 Chemical Sensor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-11-27 US disclosed