Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20818634 | 0.91 | CYP3A4 (0.58) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL30476445 | 0.91 | CYP3A4 (0.58) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL31071488 | 0.86 | CYP3A4 (0.71) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL15093706 | 0.86 | CYP3A4 (0.71) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL5410711 | 0.86 | ATM (0.50) | GPR119MGLLKDM4EALDH1A1TSHR | |
| SCHEMBL210120 | 0.85 | CYP3A4 (0.61) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL29363322 | 0.83 | CYP3A4 (0.59) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL19668681 | 0.83 | CYP3A4 (0.59) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL8473520 | 0.80 | CYP3A4 (0.53) | CYP3A4CYP3A5GPR119PLA2G7MGLL | |
| SCHEMBL8473516 | 0.80 | CYP3A4 (0.53) | CYP3A4CYP3A5GPR119PLA2G7MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134036-A1 | ALPHA-SUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-α]PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |