Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | OGA | O60502 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035319 | 0.84 | CHRM2 (0.45) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL14035226 | 0.84 | CHRM2 (0.45) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL14035317 | 0.83 | CHRM2 (0.49) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL8458368 | 0.83 | CHRM2 (0.49) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL14035488 | 0.83 | CHRM2 (0.49) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL5133764 | 0.79 | HRH3 (0.35) | ALDH1A1 | |
| SCHEMBL4102926 | 0.79 | HRH3 (0.35) | ALDH1A1 | |
| SCHEMBL4094000 | 0.79 | HRH3 (0.35) | ALDH1A1 | |
| SCHEMBL14035277 | 0.78 | CHRM2 (0.35) | CHRM2CHRM1MEN1KMT2ACYP2D6 | |
| SCHEMBL14035268 | 0.78 | CHRM2 (0.35) | CHRM2CHRM1MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134036-A1 | ALPHA-SUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-α]PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |