Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 4/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094000 | 1.00 | HRH3 (0.35) | HRH3XIAPBIRC2CHRM4KDM4E | |
| SCHEMBL4102926 | 1.00 | HRH3 (0.35) | HRH3XIAPBIRC2CHRM4KDM4E | |
| SCHEMBL4982738 | 0.86 | HRH3 (0.38) | HRH3XIAPBIRC2CACNA2D1OPRM1 | |
| SCHEMBL4107027 | 0.86 | HRH3 (0.38) | HRH3XIAPBIRC2CACNA2D1OPRM1 | |
| SCHEMBL4100180 | 0.86 | HRH3 (0.38) | HRH3XIAPBIRC2CACNA2D1OPRM1 | |
| SCHEMBL4093102 | 0.85 | HRH3 (0.39) | HRH3XIAPBIRC2CACNA2D1OPRM1 | |
| SCHEMBL4094531 | 0.85 | HRH3 (0.39) | HRH3XIAPBIRC2CACNA2D1OPRM1 | |
| SCHEMBL4099431 | 0.81 | HRH3 (0.34) | HRH3XIAPBIRC2 | |
| SCHEMBL5133237 | 0.81 | HRH3 (0.34) | HRH3XIAPBIRC2 | |
| SCHEMBL4097155 | 0.81 | HRH3 (0.34) | HRH3XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134036-A1 | ALPHA-SUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-α]PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |