SCHEMBL14035538

SCHEMBL14035538

Cc1cccnc1N1CC=C(C(=O)Nc2ccc(C(C)C)cc2)CC1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 18/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4873167 0.90 TRPV1 (0.81) TRPV1
SCHEMBL13743110 0.86 TRPV1 (0.80) TRPV1
SCHEMBL12149479 0.85 TRPV1 (0.81) TRPV1
SCHEMBL12689886 0.82 TRPV1 (1.00) TRPV1
SCHEMBL4873173 0.81 TRPV1 (0.84) TRPV1
SCHEMBL4868027 0.79 TRPV1 (1.00) TRPV1
SCHEMBL10323906 0.78 TRPV1 (0.81) TRPV1
SCHEMBL4546343 0.78 TRPV1 (0.85) TRPV1
SCHEMBL6430270 0.78 TRPV1 (0.79) TRPV1
SCHEMBL4874196 0.77 TRPV1 (0.84) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1862458-B1 Therapeutic agents useful for treating pain EURO CELTIQUE SA (LU) 2008-11-05 EP disclosed