Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873173 | 0.90 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL4868027 | 0.89 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4546343 | 0.88 | TRPV1 (0.85) | TRPV1 | |
| SCHEMBL4873167 | 0.88 | TRPV1 (0.81) | TRPV1 | |
| SCHEMBL4869732 | 0.88 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL4874196 | 0.88 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL4546333 | 0.87 | TRPV1 (0.82) | TRPV1 | |
| SCHEMBL1253235 | 0.87 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4866225 | 0.87 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL4994316 | 0.87 | TRPV1 (0.79) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748610-B2 | Compounds as TRPV1 antagonists, pharmaceutical compositions and medical uses thereof | FL THERAPEUTICS LLC (US) | 2014-06-10 | — | — | US | disclosed |
| US-8748610-B2 | Compounds as TRPV1 antagonists, pharmaceutical compositions and medical uses thereof | FL THERAPEUTICS LLC (US) | 2014-06-10 | — | — | US | disclosed |
| US-8748610-B2 | Compounds as TRPV1 antagonists, pharmaceutical compositions and medical uses thereof | FL THERAPEUTICS LLC (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120184509-A1 | Compounds as TRVP1 Blockers, Pharmaceutical Compositions and Medical Uses Thereof | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2012-07-19 | — | — | US | disclosed |
| US-20120184509-A1 | Compounds as TRVP1 Blockers, Pharmaceutical Compositions and Medical Uses Thereof | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184509-A1 | Compounds as TRVP1 Blockers, Pharmaceutical Compositions and Medical Uses Thereof | TRPV1, TRPV4, TRPV3 | TRPV1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.