Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.69 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.68 |
| ▸ | FABP3 | P05413 | 1/20 | 0.62 |
| ▸ | FABP4 | P15090 | 1/20 | 0.62 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.59 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.59 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MYC | P01106 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133057 | 1.00 | HNF4A (0.69) | HNF4ABCAT2FABP3FABP4FABP5 | |
| Benzene SCHEMBL28480917 | 1.00 | HNF4A (0.69) | HNF4ABCAT2FABP3FABP4FABP5 | |
| SCHEMBL26624744 | 1.00 | HNF4A (0.69) | HNF4ABCAT2FABP3FABP4FABP5 | |
| SCHEMBL8872993 | 0.98 | HNF4A (0.67) | HNF4ABCAT2FABP3FABP4FABP5 | |
| Biphenyl SCHEMBL9292498 | 0.98 | HNF4A (0.67) | HNF4ABCAT2FABP3FABP4FABP5 | |
| SCHEMBL7407371 | 0.98 | HNF4A (0.73) | HNF4ABCAT2FABP3FABP4FABP5 | |
| SCHEMBL17371707 | 0.98 | HNF4A (0.67) | HNF4ABCAT2FABP3FABP4FABP5 | |
| Fluoride SCHEMBL11030268 | 0.98 | HNF4A (0.67) | HNF4ABCAT2FABP3FABP4FABP5 | |
| SCHEMBL8615784 | 0.98 | HNF4A (0.67) | HNF4ABCAT2FABP3FABP4FABP5 | |
| Ammonia Solution, Strong SCHEMBL27350797 | 0.98 | HNF4A (0.67) | HNF4ABCAT2FABP3FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370244-A1 | METAL-ORGANIC FRAMEWORK | The University of Liverpool (GB) | 2024-05-22 | — | — | EP | disclosed |
| US-20230178848-A1 | ELECTRODE SEPARATORS | UNIV KING ABDULLAH SCI & TECH (SA) | 2023-06-08 | — | — | US | disclosed |
| US-20230151028-A1 | High Yield Synthesis Of Metal-Organic Frameworks | ExxonMobil Technology and Engineering Company | 2023-05-18 | — | — | US | disclosed |
| US-11643372-B2 | Method of using metal organic framework | PHILLIPS 66 COMPANY (US) | 2023-05-09 | — | — | US | disclosed |
| EP-4139321-A1 | HIGH YIELD SYNTHESIS OF METAL-ORGANIC FRAMEWORKS | ExxonMobil Technology and Engineering Company (US) | 2023-03-01 | — | — | EP | disclosed |
| WO-2023285834-A1 | METAL-ORGANIC FRAMEWORK | THE UNIVERSITY OF LIVERPOOL (GB) | 2023-01-19 | — | — | WO | disclosed |
| WO-2022081654-A1 | METHOD OF USING METAL ORGANIC FRAMEWORK | PHILLIPS 66 COMPANY (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081633-A1 | METHOD OF USING METAL ORGANIC FRAMEWORK | PHILLIPS 66 COMPANY (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081647-A1 | METHOD OF USING METAL ORGANIC FRAMEWORK | PHILLIPS 66 COMPANY (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022081641-A1 | METAL ORGANIC FRAMEWORK | PHILLIPS 66 COMPANY (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2017050936-A1 | PROCESS | UNIVERSITETET I OSLO (NO) | 2017-03-30 | — | — | WO | disclosed |
| US-9474997-B1 | Metal-organic framework sorbents having hierarchical pore structure and method of making the same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2016-10-25 | — | — | US | disclosed |
| WO-2016046383-A1 | PROCESS FOR PREPARING A ZIRCONIUM-BASED METAL ORGANIC FRAMEWORK | UNIVERSITETET I OSLO (NO) | 2016-03-31 | — | — | WO | disclosed |
| US-9114348-B2 | Metal organic framework compounds | UNIVERSITETET I OSLO (NO) | 2015-08-25 | — | — | US | disclosed |
| US-20140322123-A1 | METAL ORGANIC FRAMEWORK COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2014-10-30 | — | — | US | disclosed |
| US-8653292-B2 | Metal organic framework compounds | UNIVERSITETET I OSLO (NO) | 2014-02-18 | — | — | US | disclosed |
| EP-2291384-B1 | METAL ORGANIC FRAMEWORK COMPOUNDS | UNI I OSLO (NO) | 2013-09-04 | — | — | EP | disclosed |
| US-20120115961-A1 | METAL ORGANIC FRAMEWORK COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2012-05-10 | — | — | US | disclosed |
| EP-2291384-A2 | METAL ORGANIC FRAMEWORK COMPOUNDS | Universitetet I Oslo (NO) | 2011-03-09 | — | — | EP | disclosed |
| WO-2009133366-A2 | METAL ORGANIC FRAMEWORK COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151028-A1 | High Yield Synthesis Of Metal-Organic Frameworks | MAX, POF1B, CPSF1 | HNF4A 610/4885BCAT2 1802/4885FABP3 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.