SCHEMBL14035707

SCHEMBL14035707

Cc1ccc(C23CC4CC(CC(COC(=O)C(F)(F)OOS)(C4)C2)C3)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
EPHX2 P34913 1/20 0.32
ALDH1A1 P00352 2/20 0.31
USP2 O75604 1/20 0.31
HPGD P15428 1/20 0.31
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14035708 0.87 MEN1 (0.34) KMT2AMEN1LMNAGAAHTT
SCHEMBL685825 0.87 KMT2A (0.43) KMT2AMEN1LMNAGAAHTT
SCHEMBL14035706 0.86 KMT2A (0.49) KMT2AMEN1LMNAGAAHTT
SCHEMBL14035713 0.85 KMT2A (0.33) KMT2AMEN1LMNAGAAHTT
SCHEMBL687190 0.84 KMT2A (0.37) KMT2AMEN1LMNAGAAHTT
SCHEMBL14009394 0.83 KMT2A (0.36) KMT2AMEN1LMNAGAAHTT
SCHEMBL2603087 0.81 KMT2A (0.35) KMT2AMEN1LMNAGAAHTT
SCHEMBL14035731 0.80 MEN1 (0.42) KMT2AMEN1LMNAGAAHTT
SCHEMBL14035715 0.80
SCHEMBL14035705 0.79 KMT2A (0.32) KMT2AMEN1LMNAGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274426-A1 Using acrylic ester and sulfonium said salt; high resolution semiconductors; microfabrication patterns; excimer laser lithography SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 US disclosed