SCHEMBL14035708

SCHEMBL14035708

Cc1cc(C)c(C23CC4CC(CC(COC(=O)C(F)(F)OOS)(C4)C2)C3)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
EPHX2 P34913 1/20 0.31
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14035707 0.87 KMT2A (0.36) MEN1KMT2AUSP2ALDH1A1LMNA
SCHEMBL686252 0.86 MEN1 (0.41) MEN1KMT2AUSP2ALDH1A1LMNA
SCHEMBL14035706 0.85 KMT2A (0.49) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL14035705 0.83 KMT2A (0.32) MEN1KMT2ALMNAGAAHTT
SCHEMBL686584 0.83 MEN1 (0.34) MEN1KMT2AUSP2ALDH1A1LMNA
SCHEMBL14009391 0.82 MEN1 (0.34) MEN1KMT2AUSP2ALDH1A1LMNA
SCHEMBL2603089 0.80 MEN1 (0.33) MEN1KMT2AUSP2ALDH1A1LMNA
SCHEMBL14035713 0.80 KMT2A (0.33) MEN1KMT2AUSP2ALDH1A1LMNA
SCHEMBL14035731 0.80 MEN1 (0.42) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL14035716 0.79 HSD11B1 (0.44) MEN1KMT2AALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274426-A1 Using acrylic ester and sulfonium said salt; high resolution semiconductors; microfabrication patterns; excimer laser lithography SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 US disclosed