Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.43 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.43 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.43 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.43 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.43 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245446 | 0.94 | BDKRB2 (0.46) | BDKRB2MCHR1ADCY6ADCY3ADCY9 | |
| SCHEMBL13365364 | 0.93 | HDAC1 (0.46) | BDKRB2MCHR1ADCY6ADCY3ADCY9 | |
| SCHEMBL12341121 | 0.92 | BDKRB2 (0.42) | BDKRB2MCHR1ADCY6ADCY3ADCY9 | |
| SCHEMBL5018245 | 0.91 | BDKRB2 (0.44) | BDKRB2MCHR1ADCY6ADCY3ADCY9 | |
| SCHEMBL10084093 | 0.90 | BDKRB2 (0.41) | BDKRB2MCHR1ADCY6ADCY3ADCY9 | |
| SCHEMBL10084118 | 0.90 | BDKRB2 (0.43) | BDKRB2MCHR1ADCY6ADCY3ADCY9 | |
| SCHEMBL5018129 | 0.89 | MCHR1 (0.43) | BDKRB2MCHR1ADCY6ADCY3ADCY9 | |
| SCHEMBL10084251 | 0.88 | BDKRB2 (0.42) | BDKRB2MCHR1ADCY6ADCY3ADCY9 | |
| SCHEMBL5018225 | 0.88 | BDKRB2 (0.43) | BDKRB2MCHR1ADCY6ADCY3ADCY9 | |
| SCHEMBL12341120 | 0.88 | BDKRB2 (0.43) | BDKRB2MCHR1ADCY6ADCY3ADCY9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141012-A2 | QUATERNARY ALKYL AMMONIUM BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |