Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035986 | 0.96 | HDAC1 (0.47) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1246051 | 0.93 | HDAC1 (0.49) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1244303 | 0.93 | HDAC1 (0.49) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1245469 | 0.93 | HDAC1 (0.49) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1246389 | 0.93 | HDAC1 (0.49) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1245391 | 0.92 | HDAC1 (0.50) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1245389 | 0.91 | RAB9A (0.50) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL12341122 | 0.91 | HDAC1 (0.45) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5018448 | 0.90 | MAPT (0.46) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10084119 | 0.89 | MAPT (0.44) | HDAC1HDAC4MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141012-A2 | QUATERNARY ALKYL AMMONIUM BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |